6 Uses of Dapoxetine: Side Effects + Precautions

Dapoxetine is the first compound developed for the treatment of premature ejaculation in men. It is useful for age group of 18 to 64 years. Brand name for it is Priligy. It can also be used as an  anti-depressant ,  but the body absorbs and eliminates it too quickly . Due to this it is better suitable for treatment of premature ejaculation . Premature ejaculation is a major issue in male sexual health. It is a common sexual dysfunction shared by many men.

HISTORY OF DAPOXETINE:

Eli Lilly pharmaceuticals was the first company to create Dapoxetine. It was handed over to Johnson & Johnson in 2003. They submitted it as a new drug application to FDA for the treatment of PE in 2004. Menarini got the right in 2012, for  commercial basis in Africa and Asia .Later in  Latin America and the Middle East too.

WORKING OF DAPOXETINE:

Dapoxetine working is unclear. It is short acting selective serotonin inhibitor (SSRI). Serotonin is a chemical found in human body. It is present in the brain, bowels and blood platelets. It carries signal along and between the nerves. According to some scientist, it is useful for maintaining mood balance. Evidence shows that Dapoxetine  increase the discharge of semen latency time. Patient experience clear outcomes. Showing greater control over discharge of semen. It is ideal for on demand dosing. It is first and only licensed drug to treat PE in men aged 18 to 64 years.

6 USES OF DAPOXETINE:

1. It is an anti-depressant
2. It is useful in treatment of PE in men.
3. Increases the activity of serotonin in the Nervous system
4. It improve increase time to release of semen in the interior of vagina.
5. They provide sexual satisfaction in patients
6. Decreased adverse effects as compared to other medicines.

DOSAGES OF DAPOXETINE:

1. It comes in two forms -30 mg or 60 mg tablets.
2. Start with 30 mg tablet and can raise to 60 mg if needed.
3. Take it 1 to 3 hours prior to sexual activity
4. Don’t break or chew the pill. Swallow it with water.
5. Take maximum of one pill in a day.
6. The safe and efficacy is unexplained for men 65 and above.

COMMON SIDE EFFECTS OF DAPOXETINE:

It will show withdrawal symptoms if stopped at once. So it is necessary to decrease the dose slowly. Many side effects given below decreases with continued treatment. It does not need any cessation of therapy.

1. Nausea
2. Dizziness
3. Headache
4. Diarrhea
5. Fatigue
6. Insomnia
7. Sedation

If one continues for long term use, its efficacy on the body decreases.

Other side effects that require counseling are as follows;

1. AV block or sick syndrome
2. History of severe depression
3. History of syncope
4. Sensitive to active ingredient

PRECAUTIONS BEFORE TAKING DAPOXETINE:

It is necessary to take care in certain conditions as discussed below

1. It isn’t advised for patient with severe renal impairment
2. In Hepatic impairment
3. Inform your doctor regarding current medicine you take

COSTS OF DAPOXETINE VS PRILLIGY:

Generic drugs are cheaper and as effective as their brand named counterpart . They both contain the same active ingredient. We can see a vast difference in their charges. For example, generic Dapoxetine 60 mg costs $ 3.82 per pill. And the cost of brand Priligy manufactured in USA will cost you up to  $ 42.67 per pill.