Imiquimod is a patient-applied cream. It is prescribed to treat genital warts, basal cell carcinoma, and actinic keratosis. The cream gives relief from skin damage in case of the above problems. The Imiquimod cream is available worldwide as of 2015.
Imiquimod is in the class of medication called as Immune response modifier. It acts as a toll-like receptor-T agonist. It works by stimulating innate and acquired immune response. That means it stimulates natural killer cells and the proliferation of B-cells. This lead to the inflammatory cell infiltration where the cream is applied. The process is followed by apoptosis (programmed cell death) of diseased tissue.
It is thought that the cream helps to activate your immune system to fight abnormal precancerous skin growth. It reduces HPV types 6 and 11 viral loads with wart regression. It also activates cytotoxic T lymphocytes. These cells provide long-term immune memory. This, in turn, offers future protection against a repetition of previous virus or tumor. Thus it shows antitumor activity. It helps the patient’s body to destroy genital warts, AKs and cancer cells.
Imiquimod cream is not for oral, ophthalmic or intravaginal use. It is available in the form of sachets of strength 5% (0.25 mg). The dosage is different for the three different conditions.
Both of them contain the same active ingredient. So, they show the same effect. Price differs due to the brand name of the company, packaging, and pricing. Bulk sources of raw material reduce the rates of generic medicines. Many other cost-saving measures are also applied. This reduces the cost of generic medicines.
Cost of Generic Imiquimod cream,
The cost of a 12 packets of 5 % (0.25 mg) is $ 80, per unit cost is $ 6.67.
Cost of brand Aldara,
The cost of a 12 packets of 5 % (0.25 mg) is $ 1,024.87, per unit cost is $ 85.40.