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Medication that Treats Acute Worsening of Chronic Bronchitis

Moxifloxacin HCl is an antibiotic. It treats bacterial infections like pneumonia and others. It is a broad spectrum antibacterial drug. It treats a range of bacterial disease. It received approval from FDA in 1999 in the United States.

How do the Moxifloxacin HCl works?

The drug belongs to the class of anti-biotics called as fluoro-quinolones. This will not work on viral infections.

  • DNA gyrase and topoisomerase enzymes are responsible for
  1. DNA replication.
  2. Transcription.

iii.    Partitioning of chromosomal DNA.

  1. DNA repair during the division of the bacterial cell.
  • The above drug binds with this enzymes and inhibits its activity.
  • This prevents the replication, repair, and separation of DNA.
  • By this process, it stops bacterial growth and reproduction. This kills the bacteria.

How to take Moxifloxacin?

  1. The drug is available in the form of a tablet of strength 400 mg.
  2. The General dose is 400 mg (single tablet) one time in a day.
  3. The time of treatment depends on the type of infection. Generally, it is between 5-14 days comment.
  4. You can take a tablet with or without food.
  5. Use in children may cause permanent injury to muscles and bones.
  6. Safety and efficacy for children <18 years is unknown.

What are the uses of Moxifloxacin HCl?

  • It is an antibiotic used in wide range of bacterial infection.
  • FDA has approved it for the treatment of bacterial infections like
  1. Acute worsening of chronic bronchitis.
  2. Pneumonia
  3. Plague
  4. Conjunctivitis
  • It is also useful in bacterial infections of
  1. Skin
  2. Abdomen
  3. Acute Sinus Infections
  • Treats pneumonia in HIV patients.
  • It may be used for other reasons not indicated in medication guide.

What are the precautions in taking Moxifloxacin HCl?

It is important to consider certain conditions.

  • NSAIDs class may increase the risk of CNS stimulation and convulsions’.
  • Safety and efficacy in case of children under age of 18 are not established.
  • Don’t use in combination with a corticosteroid.
  • Don’t use with Antacids that contain aluminum and magnesium iron. It will reduce absorption of above drug.
  • No well-controlled studies show safety to use of above drug in pregnancy and in breastfeeding.
  • Take to your Doctor if you have/are,
    • Allergy to above drug.
    • Any other allergies.
    • Diarrhea
    • Severe kidney problems.
    • Sunburn
    • Diabetic patient.
    • History of organ transplant.

Inform your doctor about all other medicines you take to avoid drug interactions.

Cost of Moxifloxacin HCl (Generic & Brand)

Generic and brand drug show same basic active ingredient. They differ in their price. Generic medicines are cheaper than Brand ones. Brand companies spend a big amount of research and development of the product. They have to pay for advertising, packaging & pricing of the drug. Generic medicines do not spend much on these things.

  • Cost of Generic Moxifloxacin HCL.

10 tabs of 400 mg costs $ 55, per unit cost, is $ 5.5.

  • Cost Brand Avelox.

10 tabs of 400 mg costs $ 242.21, per unit cost, is $ 24.22.

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