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Medication that Treats Acute Worsening of Chronic Bronchitis

Moxifloxacin HCl is an antibiotic. It treats bacterial infections like pneumonia and others. It is a broad spectrum antibacterial drug. It treats a range of bacterial disease. It received approval from FDA in 1999 in the United States.

Moxifloxacin 400mg

How do the Moxifloxacin HCl works?

The drug belongs to the class of anti-biotics called as fluoro-quinolones. This will not work on viral infections.

  • DNA gyrase and topoisomerase enzymes are responsible for
  1. DNA replication.
  2. Transcription.

iii.    Partitioning of chromosomal DNA.

  1. DNA repair during the division of the bacterial cell.
  • The above drug binds with this enzymes and inhibits its activity.
  • This prevents the replication, repair, and separation of DNA.
  • By this process, it stops bacterial growth and reproduction. This kills the bacteria.

How to take Moxifloxacin?

  1. The drug is available in the form of a tablet of strength 400 mg.
  2. The General dose is 400 mg (single tablet) one time in a day.
  3. The time of treatment depends on the type of infection. Generally, it is between 5-14 days comment.
  4. You can take a tablet with or without food.
  5. Use in children may cause permanent injury to muscles and bones.
  6. Safety and efficacy for children <18 years is unknown.

What are the uses of Moxifloxacin HCl?

  • It is an antibiotic used in wide range of bacterial infection.
  • FDA has approved it for the treatment of bacterial infections like
  1. Acute worsening of chronic bronchitis.
  2. Pneumonia
  3. Plague
  4. Conjunctivitis
  • It is also useful in bacterial infections of
  1. Skin
  2. Abdomen
  3. Acute Sinus Infections
  • Treats pneumonia in HIV patients.
  • It may be used for other reasons not indicated in medication guide.

What are the precautions in taking Moxifloxacin HCl?

It is important to consider certain conditions.

  • NSAIDs class may increase the risk of CNS stimulation and convulsions’.
  • Safety and efficacy in case of children under age of 18 are not established.
  • Don’t use in combination with a corticosteroid.
  • Don’t use with Antacids that contain aluminum and magnesium iron. It will reduce absorption of above drug.
  • No well-controlled studies show safety to use of above drug in pregnancy and in breastfeeding.
  • Take to your Doctor if you have/are,
    • Allergy to above drug.
    • Any other allergies.
    • Diarrhea
    • Severe kidney problems.
    • Sunburn
    • Diabetic patient.
    • History of organ transplant.

Inform your doctor about all other medicines you take to avoid drug interactions.

Cost of Moxifloxacin HCl (Generic & Brand)

Generic and brand drug show same basic active ingredient. They differ in their price. Generic medicines are cheaper than Brand ones. Brand companies spend a big amount of research and development of the product. They have to pay for advertising, packaging & pricing of the drug. Generic medicines do not spend much on these things.

  • Cost of Generic Moxifloxacin HCL.

10 tabs of 400 mg costs $ 55, per unit cost, is $ 5.5.

  • Cost Brand Avelox.

10 tabs of 400 mg costs $ 242.21, per unit cost, is $ 24.22.

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