Chloroquine is a generic drug primarily prescribed for either prevention or treatment of malaria and autoimmune diseases. It has been used for more than 70 years and is considered safe and effective. It’s prescribed to both adults and children of all ages. It’s even safe for pregnant or nursing mothers.
Recently, Chloroquine phosphate has been sporadically used in treating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections which causes the coronavirus disease 2019 or COVID-19. This disease, now a pandemic disease, is an infectious disease that was first identified in Wuhan, China in 2019. Common symptoms include cough, fever, and shortness of breath. Sputum production, muscle pain, and sore throat are less common. While the majority of symptoms are mild, some progress to pneumonia and multiple organ failure with a death rate of 1% to 5%. There is no current vaccine or specific antiviral treatment for coronavirus disease.
That being said, researchers have discovered that Chloroquine phosphate is effective in fighting the SARS-CoV-2 virus that causes COVID-19. It is believed that this drug has a broad spectrum of antiviral action, although it is not approved as an antiviral agent. In vitro experiments, Chloroquine blocks the virus infection by changing the acidity and basicity value inside the cells and the interfering receptors of SARS coronavirus. Chloroquine phosphate also shows immune-modulating activity, which may enhance its antiviral effect. It’s widely distributed in the whole body including the lung after intake. Researchers are currently looking at the potential of this drug in combating coronavirus disease.
The multicentre collaboration group of Health Commissions and the Department of Science and Technology in Guangdong Province of China have developed their expert consensus in the use of Chloroquine among patients with coronavirus pneumonia disease after an extensive discussion. The recommended dose for patients diagnosed with mild, moderate and severe cases of coronavirus disease is 500mg of Chloroquine tablet two times a day for 10 days.
So far, among the COVID-19 patients enrolled in the clinical trials, no obvious serious adverse reaction related to Chloroquine has been reported.
Things to Remember
Based on the clinical trials done by Chinese experts in Beijing, Chloroquine Phosphate, an antimalarial drug, has shown fairly good efficacy against the corona virus-19. It has shown certain curative effects on the novel coronavirus disease or COVID-19. Chloroquine, which has been used for more than 70 years, was selected from tens of thousands among existing drugs after multiple rounds of screening. In the different trials conducted, Chloroquine drug has shown better indicators than their parallel group in terms of:
On a recent video conference held by experts which include the Ministry of Science and Technology, National Health Commission and the National Medical Products Administration, have agreed that Chloroquine Phosphate can be used to treat COVID-19 patients. It is important to consult your doctor before buying this.
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