Cyclosporine is a cyclic polypeptide with 11 amino acids obtained from a fungus. This medicine specifically inhibits proliferation of T- lymphocyte cells, production of interleukin and cytokines. In cell mediated immunity antigen is processed and presented to helper T-cells. This secretes interleukins and cytokines that cause proliferation cytotoxic lymphocytes. The mature cytotoxic lymphocytes (killer cells) lyse antigen-containing cells. This medicine selectively suppresses cell-mediated immunity and prevents graft rejection. It suppresses the responses of primed helper T-cells also and hence used in the treatment of autoimmune diseases. It does not affect the bone marrow and reticuloendothelial system. It is more active when administered before antigen exposure. Now you can buy Cyclosporine here at Rx 2 Go Pharmacy.
Cyclosporine inhibits cell mediated immunity system. The stimulation of T-cells produces a cascade of calcium dependent events and protein kinase activation. The calcium ions binding to calmodulin activate calcineurin, which dephosphorylates regulatory proteins. This medicine enters target cells and binds to a protein called cyclophilin. This complex then binds to and inactivates calcineurin thus inhibiting antigen stimulated activation and proliferation of T-cells.
The common side effects reported with Cyclosporine are ocular burning, conjuctival hyperemia, discharge, epiphora, eye pain, foreign body sensation, pruritis, stinging and visual disturbance.
The bottle containing Cyclosporine should be inverted before use to form an opaque, uniform white emulsion. It can be used along with artificial tears. The artificial tears should be administered 15 min after this medicine administration. The patient should be advised not to use contact lenses while administering this ophthalmic drops. The contact lens can be worn 15 minutes after it is administered. It is not advisable to use this medication during pregnancy and lactation. If it is an absolute must to use this medicine during pregnancy and lactation, it should be administered under the supervision of a medical practitioner. It is not administered in pediatric patients below the age of 16.
Restasis ophthalmic drops should be administered one drop twice daily.
The active ingredient is Cyclosporine in both brand and generic forms because of which the mechanism of action and drug interactions are the same. The difference between brand and generic forms are packaging, pricing and the brand name. Generic variants are priced cheaper because there are no brand names associated with it as well as no expenses towards research and development. You can buy cheap Restasis pills when it is sold as a generic variant.
You can purchase Cyclosporine medicine online from our pharmacy. When you order this drug online from us, it will reach your doorstep without any hassles. You can also save more when you buy this medicine online in more numbers with the volume discounts we offer.
At Rx 2 Go Pharmacy, we sell generic Cyclosporine, which means that we do not have to spend heavily on research and development of the drug. We also source the drugs directly from the manufacturer thereby eliminating any additional costs such as commissions to agents etc. All the savings accrued through various measures translates to the cheaper price of generic prescription drugs at Rx 2 Go Pharmacy. You can also get additional price benefits by taking advantage of the volume discounts we offer.
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