Linezolid is active against methicillin resistant and vancomycin resistant Staphylococcus aureus, vancomycin resistant enterococci, penicillin resistant Streptococcus pyogens, Streptococcus viridians, corynebacterium and listeria. Zyvox is primarily bacteriostatic, but bactericidal against some streptococci and B.fragilis. Zyvox is used for uncomplicated and complicated skin and soft tissue infections, community and hospital acquired pneumonia, bacteremias and other drug resistant gram-positive bacterial infections. Zyvox is not useful for the treatment of enterococcal endocarditis. You can easily buy Linezolid at Rx 2 Go Pharmacy.
Linezolid inhibits bacterial protein synthesis by binding to 23S fraction of 50S ribosome and interferes with formation of the ternary N-formylmethionine-tRNA-70S complex. The binding of Linezolid distorts the tRNA site overlapping both 50S and 30S ribosomal subunits and stops protein synthesis before it starts.
The common side effects reported with Linezolid are diarrhea, nausea, head ache, vomiting, insomnia, constipation, rash, dizziness, fever, taste alteration, abnormal liver function tests, tongue discolouration, vaginal moniliasis and oral moniliasis.
The concomitant use of Linezolid with adrenergic and serotonergic agents is not recommended. Zyvox can cause lactic acidosis and convulsions. Zyvox when administered along with selective serotonin reuptake inhibitors (SSRIs) can cause serious serotonin syndrome. The long term use of Linezolid can cause peripheral and optic neuropathy. The prolonged use of Zyvox can result in the development of superinfection. It is not advisable to consume the Linezolid during pregnancy and lactation. Linezolid should not be administered to patients with uncontrolled hypertension, pheochromocytoma and thyrotoxicosis. The use of directly and indirectly acting sympathomimetic agents (e.g. pseudoephedrine), vasopressive agents (e.g. epinephrine, norepinephrine), dopaminergic agents (e.g. dopamine, dobutamine) is contraindicated along with Linezolid. Linezolid can be taken without regard of food. The patient should be advised to avoid foods or beverages with high tyramine content while taking Zyvox. Zyvox should not be used in patients who are on monoamine oxidase inhibitors or within 2 weeks of discontinuing MAO inhibitors.
The recommended starting dosage of Linezolid is 600mg twice daily for 10-14 days.
The active ingredient is Linezolid in both brand and generic forms because of which the mechanism of action and drug interactions are the same. The difference between brand and generic forms are packaging, pricing and the brand name. Generic variants are priced cheaper because there are no brand names associated with it as well as no expenses towards research and development. You can buy cheap Zyvox medicine when it is sold as a generic variant.
You can purchase Zyvox medicine online from our pharmacy. When you order Zyvox drug online from us, it will reach your doorstep without any hassles. You can also save more when you buy Zyvox online in more numbers with the volume discounts we offer.
At Rx 2 Go Pharmacy, we sells generic Zyvox, which is priced lesser compared to brands because of the savings in research and development of the drug. Generic prescription drugs do not require any spending on research and development activities. We also source all drugs directly from the manufacturers and hence able to negotiate better prices on bulk orders. Among our best selling drugs and medications are; Modafinil, Tramadol, Gabapentin, Piracetam, Sumatriptan, Metoprolol Tartrate, Sildenafil Citrate, Tadalafil, Dapoxetine, Acyclovir Cream and many more.
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