Lisinopril is a lysine derivative of prodrug enaprilat. Zestril can be used alone or in combination with diuretic for the treatment of hypertension. Lisinopril oral absorption is very slow and hence does not show early vasodilator side effects. Lisinopril oral absorption is incomplete but not affected by food. Zestril is a long acting antihypertensive and this permits single daily dosing. The single daily dosing of Zestril ensures uniform hypotensive action round the clock. You can now buy Lisinopril here at Rx 2 Go Pharmacy.
Zestril is an Angiotensin converting enzyme inhibitor ACE inhibitor. ACE inhibitor inhibits the conversion of Angiotensin I to Angiotensin II. Angiotensin II is an octapeptide in plasma, which is obtained by a precursor plasma alpha globulin and is involved in electrolyte, blood volume and pressure homeostasis.
The common side effects reported with Lisinopril are orthostatic hypotension, syncope, fever, chills, malaise, cardiac arrest, palpitations, bradycardia, atrial fibrillation, peripheral edema, vomiting, gastrointestinal cramps, flatulence, dry mouth, hemolytic anemia, diabetes mellitus, weight loss, dehydration, tremor, peripheral neuropathy, bronchitis, wheezing, blurred vision and urinary tract infection.
The dose of Lisinopril should be adjusted in patients with renal impairment. If diuretic is also to be administered along with Zestril, the dose of Zestril should be reduced. The concomitant administration of Zestril and potassium supplements or potassium sparing diuretics can cause hyperkalemia. If you are taking diuretic along with Zestril there is a chance of developing hypotension. Therefore it is recommended to discontinue diuretic 2 days before Lisinopril treatment. The concomitant use of antidiabetic drugs and Zestril can precipitate hypoglycemia. The co administration of lithium and Zestril should be followed by a continuous monitoring of serum lithium levels as it can lead to lithium toxicity. It is not advisable to consume the Lisinopril during pregnancy as it can lead to fetal death. Avoid activities that require alertness when you are taking Lisinopril. Zestril is not administered in pediatric patients below the age of 6. Lisinopril should be given with caution in patients with obstructive flow from left ventricle.
The recommended starting dosage of Zestril is 10mg/day for patients with hypertension. The maximum dose of Lisinopril for treatment of hypertension is 40mg/day. The recommended starting dose of Lisinopril in pediatric patients (more than 6years) is 0.07mg/kg once daily.
The Brand and generic Zestril contains Lisinopril as the main active ingredient. The difference between brand and generic forms are packaging, pricing and the brand name. Generic variants of the drug are now easily available. The generic and brand forms acts in the same way. You can buy cheap Zestril pills when it is sold as a generic variant.
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