Metoprolol Succinate XR can be used alone or in combination with other antihypertensives. In phaeochromocytoma Metoprolol Succinate XR should not be used as initial therapy. The therapy should be started with alpha-blockers prior to the use of beta-blockers. Toprol-XL blocks selectively beta 1 receptors. Metoprolol Succinate XR is used to reduce cardiovascular complications in post myocardial infarction patients. Toprol-XL decreases the heart rate, force of contraction and cardiac output. Metoprolol Succinate XR has lower propensity to cause bronchoconstriction. Toprol-XL is safe in diabetic patients as Metoprolol do not interfere with carbohydrate metabolism. Toprol-XL has no effect on lipid profile. You can easily buy Metoprolol Succinate online at Rx 2 Go Pharmacy.
Toprol-XL decreases the total peripheral resistance and blood pressure falls. Metoprolol Succinate XR reduces the noradrenaline release from the sympathetic terminals due to beta-receptor blockade. The beta-receptor inhibition can cause a decrease in rennin release from kidney.
The common side effects reported with Toprol-XL are reversible mental depression, intensification of AV block, agranulocytosis, fever with sore throat and respiratory distress, hepatitis, vomiting, anxiety, nervousness, hallucination, impotence and taste disturbance.
Toprol-XL tablet should be swallowed whole without crushing or chewing. Metoprolol Succinate XR is not recommended in pediatric patients below the age of 6. The concomitant use of Reserpine and Metoprolol Succinate XR can cause postural hypotension. Toprol-XL should be used with caution in patients with hepatic dysfunction. Toprol-XL is also not safe for pregnant women and nursing mothers. Toprol-XL is contraindicated in severe bradycardia, sick sinus syndrome and second or third degree heart block. The patient should be advised to avoid activities that require alertness as Toprol-XL can cause dizziness.
The recommended starting dosage of Toprol-XL is 25-100mg in single dose. The maximum dose of Metoprolol Succinate XR is 400mg once daily. The dosage should be titrated over a period of 1 week. The recommended starting dose of Metoprolol Succinate XR for pediatric patients above 6 years of age is 1mg/kg administered as a single dose.
The Brand and generic Toprol-XL contains Metoprolol Succinate XR as the main active ingredient. The difference between brand and generic forms are packaging, pricing and the brand name. The generic and brand forms acts in the same way and hence the effectiveness remains the same. It is possible to buy cheap Toprol-XL pills when it is sold as a generic variant.
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