Ropinirole is used in advanced cases of Parkinsons disease along with levodopa. Patients with minimum gastrointestinal side effects better tolerate Requip drug. Requip causes lower incidence of dyskinesias and motor fluctuations. Ropinirole is now being used as monotherapy for early Parkinsons disease. Requip is orally absorbed and plasma protein bound. Requip has a terminal half-life of 6 hours. This is more long acting than levodopa, reducing the frequency of on-off effect. Ropinirole treatment can provide longer symptom free life to Parkinsons disease patients. You can now easily buy Ropinirole here at Rx 2 Go Pharmacy and enjoy superior quality drugs at the lowest prices.
Requip is selective D2/D3 receptor agonist with negligible affinity for D1 and nondopaminergic receptors. Though the exact mechanism of action remains unclear, the dopamine agonist nature is believed to be effective against Parkinsons disease.
The common side effects reported with Ropinirole during clinical trials are neuralgia, nausea, dizziness, hallucinations and episodes of daytime sleep.
Ropinirole can be taken without regard of food. Requip can be taken along with food to reduce nausea. There is no need of dosage adjustment in patients with moderate renal impairment. Requip is not administered in patients with severe renal impairment. The dose escalation should be done at a slower rate in patients with hepatic impairment. Requip can exacerbate preexisting dyskinesia when given along with levodopa. The rapid dose reduction or withdrawal of Requip can cause neuroleptic malignant syndrome characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability. Requip can cause postural hypotension with symptoms like dizziness, nausea, syncope, and sweating. Ropinirole can cause somnolence and the possibility of falling asleep while engaged in activities of daily living. The patient should be advised to avoid driving vehicles while on Ropinirole treatment. The patient should avoid taking sedatives and alcohol. The concomitant administration of Ciprofloxacin and Ropinirole is not indicated as it can alter plasma levels of Ropinirole . It is not advisable to consume the Requip drug during pregnancy. If it is an absolute must to take Requip during pregnancy, it should be administered under the supervision of a medical practitioner. Requip is not administered to nursing mothers.
The recommended starting dosage of Ropinirole for Parkinsons disease is 0.25 mg/day given in three times daily. The maximum dose of Requip is 1mg/day taken in three times daily. The dose of Ropinirole in restless legs syndrome is 0. 25 mg taken once daily 1-3 hours before bed time. The dose can be increased to a maximum of 4mg/day.
The Brand and generic Requip contains same Ropinirole as the active ingredient. The brand and generic form differs only in price, packaging and in their names. In cost comparison, generic version of the drug is always cheaper in cost and it uses same excipients as that of brand form. The mechanism of action is same for both generic and brand forms. It is possible to buy the generic variant at a cheaper price.
The active ingredient is Ropinirole in both brand and generic forms because of which the mechanism of action and drug interactions are the same. The difference between brand and generic forms are packaging, pricing and the brand name. Generic variants are priced cheaper because there are no brand names associated with it as well as no expenses towards research and development. You can purchase cheap Requip medicine when it is sold as a generic variant.
At Rx 2 Go Pharmacy, there is a continuous improvisation on means to save costs. Our expenses towards research and development are also practically nil. We source the prescription drugs directly from the manufacturers and the price befits on bulk ordering are directly passed on to customers.
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