Roxithromycin is a broad spectrum, semi-synthetic acid stable macrolide antibiotic. Rulide is used in the treatment of upper respiratory tract infections like acute pharyngitis, tonsillitis and sinusitis; lower respiratory tract infections like acute bronchitis, chronic bronchitis, acquired pneumonia and non-gonococcal urethritis. Roxithromycin is orally administered and exhibit good tissue penetration. Rulide has long half-life making it useful for twice daily dosing. Roxithromycin has better gastric tolerability in comparison to other macrolides. Rulide is a commonly available drug and you can buy Roxithromycin here at Rx 2 Go Pharmacy.
Roxithromycin acts by inhibiting bacterial protein synthesis. Roxithromycin combines with 50S ribosome subunits and interferes with the translocation process. Rulide inhibits the movement of new peptide to peptidyl site and thus ribosome fails to move along the messenger RNA. Thus peptide chain formation gets terminated and protein synthesis is suppressed. This mechanism of action prevents the further multiplication of bacterial cells.
The common side effects reported with Roxithromycin are nausea, vomiting, diarrhea, epigastric pain, flatulence, head ache, dizziness, malaise, moniliasis or candidiasis, urticaria, rash, pruritis, angioedema and increase in serum transaminase levels. The increase in serum transaminase levels is seen especially in elderly patients.
The Roxithromycin treatment can cause hepatic dysfunction. It is recommended that the total daily dosage be reduced in patients with hepatic or renal insufficiency. The prolonged use of Rulide can result in the growth of non-susceptible organisms like fungi It is not advisable to consume Roxithromycin during pregnancy and lactation. Rulide is contraindicated along with ergotamine compounds. Caution has to be exercised when Rulide is co-administered with drugs such as terfenadine, cisapride, disopyramide, warfarin, digoxin, theophylline, midazolam and cyclosporine.
The recommended dosage of Rulide is 300mg once daily or 150mg twice daily. The recommended dosage for pediatric patients is 5-8mg/kg/day administered twice daily as divided doses.
Brand and generic Rulide contains Roxithromycin as the active ingredient and hence the effective is the same. The difference between brand and generic forms are packaging, pricing and the brand name. The mechanism of action is same for both generic and brand forms. You can buy cheap Rulide pills when it is sold as a generic variant.
You can purchase Rulide medicine online from our pharmacy. When order Rulide drug online from us, it will reach your doorstep without any hassles. You can also save more when you buy Rulide online in more numbers with the volume discounts we offer.
At Rx 2 Go Pharmacy we are always working out methods to save costs. Our costs towards research and development are zero, since we sell only generic drugs. We source the prescription drugs directly from the manufacturers and also order in bulk volume. All the savings from the various methods adopted translate to cheap prices of our drugs.
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