Spironolactone is a steroid chemically similar to aldosterone. Aldactone increases calcium excretion by direct action on renal tubules. Spironolactone reduces blood pressure slightly. Spironolactone is used in conjunction with other diuretics to prevent potassium loss and to augment antihypertensive action. Spironolactone is more useful in cirrhotic and nephrotic edema. You can buy Spironolactone here at Rx 2 Go Pharmacy and get the guarantee of the cheapest prices all through the year.
Aldosterone acts on distal renal tubules and produce aldosterone induced proteins (AIPs) that help in sodium re-absorption and potassium secretion. Spironolactone inhibits the formation of aldosterone-induced proteins (AIPs) and thus prevents the potassium loss.
The common side effects reported with Aldactone are gastric bleeding, ulceration, gastritis, diarrhea, nausea, vomiting, gynaecomastia, fever, utricaria, agranulocytosis, hyperkalemia, mental confusion, headache, lethargy, drowsiness and renal dysfunction.
Aldactone is indicated in edema due to pathological cause in pregnancy. Spironolactone when given along with potassium supplements or Angiotensin converting enzyme inhibitors (ACE Inhibitors) and non-steroidal anti-inflammatory agents (NSAIDs) can cause dangerous hyperkalemia. Hence potassium supplements should be avoided during Spironolactone therapy. You are also cautioned of concomitant use of Aldactone and narcotics, barbiturates or alcohol as it can potentiate orthostatic hypotension. Aspirin blocks the Aldactone action by inhibiting tubular excretion. The plasma levels of digoxin are increased by Spironolactone as it increases the half-life of digoxin. Aldactone should not be given along with lithium-based drugs as it causes lithium toxicity. Spironolactone should be used with caution if you are suffering from hepatic dysfunction as it can lead to hepatic coma.
The recommended starting dosage of Aldactone in congestive heart failure is 100mg administered as a single or divided dose for 5 days. The recommended dose of Aldactone for hypertension 50 to 100mg administered as a single or divided dose. In hypokalemia induced by other diuretics 25-100mg/day of Aldactone is preferred.
The active ingredient is Spironolactone in both brand and generic forms. The difference between brand and generic forms are mainly in the way it is packed, pricing and the brand name. In comparison to brand form generic version is cheaper in cost as it does no have the brand name. The generic drug acts in the same way as the brand form. You can buy cheap Aldactone pills when it is sold as a generic variant.
You can purchase Aldactone medicine online from our pharmacy. When you order Aldactone drug online from us, it will reach your doorstep without any hassles. When you buy Aldactone online from us, you can be assured of the best quality drug at the cheapest prices.
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