Tapentadol general potency is somewhere between that of tramadol and morphine ( so medium to strong ) with an analgesic efficacy comparable to that of oxycodone despite a lower incidence of side effects. ( in other words as strong as oxycodone but without the side effects ) It is generally regarded as a moderate strength opioid (a category shared by many better-known opioids such as hydrocodone and pethidine. This is great for when tramadol is not enough to stop the pain
Tapentadol is used to treat moderate to severe pain.
The extended-release form of this medicine (Nucynta ER) is for around-the-clock treatment of pain that is not controlled by other medicines. Nucynta ER is not for use on an as-needed basis for pain.
Tapentadol may also be used for purposes not listed in this medication guide.
Get emergency medical help if you have any of these signs of an allergic reaction to tapentadol: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Like other narcotic medicines, tapentadol can slow your breathing. Death may occur if breathing becomes too weak.
Call your doctor at once if you have:
You should not use this medication if you are allergic to tapentadol, or if you have:
Do not use tapentadol if you have taken a MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline and tranylcypromine.
Tapentadol may be habit forming. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.
50 mg, 75 mg, or 100 mg orally every 4 to 6 hours depending upon pain intensity, with or without food.
On the first day of dosing, the second dose may be administered as soon as one hour after the first dose, if adequate pain relief is not attained with the first dose. Subsequent dosing is 50 mg, 75 mg, or 100 mg every 4 to 6 hours and should be adjusted to maintain adequate analgesia with acceptable tolerability. Daily doses greater than 700 mg on the first day of therapy and 600 mg on subsequent days have not been studied and are, therefore, not recommended.
Opioid naive: Initial: 50 mg twice daily (recommended interval: 12 hours); titrate in increments of 50 mg no more frequently than twice daily every 3 days to effective dose (therapeutic range: 100 to 250 mg twice daily) (maximum dose: 500 mg/day)
Brand and Generic contains same active ingredient, Tapentadol. The difference between brand and Generic variants are packaging, pricing and the brand name. Several pharmaceutical companies manufacture the Generic version after the patent for the drug expires. The mechanism of action is same for both Generic and brand forms. You can buy cheap pills when it is sold as a Generic variant.
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