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Treating Nasal and Non-Nasal Congestion Allergic Rhinitis

Desloratadine is an anti-allergic drug. The drug belongs to the category of antihistamine drugs. It controls the level of histamine and shows long-lasting effect. It was invented in U.K. for the treatment of nasal and non-nasal allergic rhinitis.

How do Desloratadine works?

Desloratadine (Clarinex) is an anti-allergic medicine. It is a second-generation tricyclic antihistamine. It acts as a selective H1   antihistamine. These functions as an inverse agonist at the histamine H1 receptor. Human mast cell release Histamine that is responsible for allergic symptoms. Desloratadine inhibits the release of histamine from human mast cell. This reduces the histamine level and in turn, reduces the symptoms of allergy.

How is Desloratadine useful?

Histamine released from mast cell of the human body is responsible for pain. Desloratadine is an antihistamine tablet that decreases its level and relieves pain. The action starts within one hour of dosing and lasts for 24 hours. It was launched for the treatment of nasal and non-nasal symptoms of seasonal allergy. But it is useful for relieving pain in another disease like.

  • Treats allergic rhinitis
  • Nasal congestion
  • Relieves heavy fever
  • Other allergy symptoms like sneezing, runny nose, and red, itchy, tearing eyes
  • Treats hives
  • Allergic skin conditions
  • No habit-forming tendencies reported

How to take Desloratadine?

Available in the strength of 5mg tablet, the dosage of this medicine is different for different patients and the types of allergy. It also depends on age and reason method to take the tablet. General dose is 5 mg per day.

Method to take the tablet:

  • Dry your hands.
  • Peel the back of the foil and remove the tablet.
  • Keep it on the top of the tongue.
  • Tablet dissolves and you may swallow it with your saliva.
  • No need to drink water or any other liquid following the tablet.
  • Use the tablet as you open the blister.  Use of this tablet isn’t recommended for children and infant until 4 years of age.

Precautions in taking Desloratadine

It is important to take precaution in certain conditions as given below;

  • There is no data providing the safe use of this drug inpatient on dialysis.
  • Patients with liver and kidney disease should take special care.
  • Inform your doctor if you are allergic to the above drug or any other medication.
  • Inform your doctor regarding other medicines you take.
  • Tell your doctor if you are pregnant or plan to be pregnant.
  • It affects the human milk. Inform your doctor if you are breastfeeding.

Difference between cost (Generic Desloratadine vs Brand Clarinex)

Both brand and generic drug contain Desloratadine as an active ingredient. The important difference in their cost is packaging, pricing and the brand name of the company. You can buy cheaper generic variant.

Cost and generic Desloratadine for 5 mg tablet per unit price is $ 0.3 and a pack of 30 tablets is $ 9. Cost of brand Clarinex 5 mg tablet per unit price is $ 5.58 & cost of a pack of 30 tablets is $ 167.48. Thus it is cheaper to buy it as a generic variant.