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Clomiphene

Clomiphene is an oral medication indicated for the treatment of infertility in women who do not ovulate. It induced ovulation in women who do not produce eggs but wish to become pregnant. Clomiphene has been used since the 1960s to induce ovulation.

Clomiphene is a type of medication known as anti-estrogen. It stimulates ovulation by blocking the action of estrogen. It blocks the estrogen receptor in the hypothalamus responsible for sending messages to the pituitary glands that make it stop releasing the hormone that controls the development and the release of an egg.

This medication is a non-steroidal estrogen that results in a more prolonged interaction with the binding proteins for the estrogen receptor. The anti-estrogen effect controls and regulates the release of regulatory hormone from the hypothalamus which allows for the normal follicle development and ovulation.

Why Buy Clomiphene?

Clomiphene is FDA-approved for medical used since 1967. It’s used as a treatment for infertility in women including those who have polycystic ovary syndrome or PCOS. Clomiphene is listed as one of the most essential medications in the World Health Organization. It’s one of the safest and most effective medications needed in the health system.

Clomiphene is also used to:

  • Increase the success rate of assisted reproductive technology.
  • Sometimes used in the treatment of male hypogonadism as an alternative to testosterone replacement therapy and the treatment of gynecomastia.
  • Treat male infertility
  • Menstrual abnormalities
  • Fibrocystic breast
  • Persistent milk production

How to Take Clomiphene?

Clomiphene comes in a tablet form for you to take orally. Take Clomiphene exactly as prescribed by your physician. The dose is usually taken 5 days in a row at the beginning of your menstrual cycle. Your doctor may prescribe one, two or three pills to take at the same time depending on how you will respond to the treatment.

Your doctor may ask you to have a transvaginal ultrasound to look at your ovarian follicles or to have your blood tested to measure the hormone levels. This will help your doctor determine when you should have your intercourse or uterine insemination. This will also help your doctor determine the appropriate dose for your next cycle.

If you don’t get pregnant after three to six cycles, it’s high time to see your specialist and move on to the next treatment.

What are the side effects of Clomiphene?

The following are common side effects associated with Clomiphene:

  • Vomiting
  • Headache
  • Stomach upset
  • Abnormal vaginal bleeding
  • Flushing
  • Difficulty sleeping

Tell your doctor if the side effects above are severe or do not go away.

Serious side effects are:

  • Weight gain
  • Blurred vision
  • Stomach swelling
  • Shortness of breath
  • Double vision
  • Stomach pain
  • Enlargement of the ovaries
  • Depression
  • Seizures
  • Stroke
  • Loss of contact with reality
  • Allergic reaction

In case of serious side effects contact your doctor right away.

We care for your safety

  • Taking Clomiphene doesn’t cause ovulation right away. It may take about 5 to 10 days after the last tablet was taken before a chain reaction that leads to ovulation happens.
  • Inform your doctor if you experience any abdominal or pelvic pain, weight gain, swelling or discomfort, breathing difficulties after taking this medication. These overstimulation symptoms can be potentially serious.
  • Be aware that this medication can increase your risk of ectopic pregnancy and multiple pregnancies if you get pregnant as a result of this treatment. Discuss with your doctor about this before taking Clomiphene. However, if you have successfully conceived after taking the treatment, your fertility treatment will not cause any problem with the normal development of the baby.
  • Do not use this medicine for more than 6 cycles of therapy as it may increase your risk of ovarian cancer.
  • Doctors do not also recommend Clomiphene for more than three to six cycles due to the decreasing pregnancy rate that happens with continued use.
  • Use Clomiphene with care among if:
    • You have polycystic ovary syndrome
    • You have endometriosis
    • You have fibroids of the uterus
    • You have a history of seizures
    • You have a raised level of triglycerides in the blood
  • Do not use Clomiphene if:
    • You have abnormal bleeding from the uterus
    • You are already pregnant
    • You have liver disease
    • You have an ovarian cyst
    • You have a tumor-like endometrial cancer whose growth is stimulated by hormones
    • You are allergic to any of its ingredients.
  • Have a pregnancy test before each course of treatment to make sure you are not pregnant.
  • Not everyone responds to Clomiphene well. Women with absent ovulation due to hypothalamic amenorrhea or low body weight, women with ovarian insufficiency or early menopause are most likely to not ovulate when taking Clomiphene.
  • Clomiphene can make the uterine lining thin. This reduces the amount and quality of the cervical mucus and can interfere with the ability of the sperm to get into the uterus and fallopian tubes.

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