Medication that Helps Prevent Strokes and Heart Attacks

Cholesterol is a fatty substance. It cannot be transported in blood on its own as insoluble in water. So, it combines with certain protein to form lipoproteins. LDL (low-density Lipoprotein) is an important carrier of cholesterol. It is termed as bad cholesterol. Increased levels of LDL-C in blood is associated with increased risk & heart disease.

The drug is used to treat high cholesterol and related conditions. It is used in combination with exercise, diet and weight loss.

How does Rosuvastatin work?

Rosuvastatin belongs to the class of medication called statins. It is also known as HMG- CoA reductase inhibitors. It is an enzyme that produces cholesterol in livers. The drug blocks the pathway for cholesterol synthesis in the liver. Most of the circulating cholesterol comes from internal Synthesis by the liver.

It is also believed that the drug seeks to compensate by producing LDL receptors to throw cholesterol out of the circulation. LDL receptors bind to LDL and VLDL particle (bad cholesterol) in the liver and they are reprocessed into bile salts and other by-products. Studies show that statin prevents CVD due to four reasons.

• Improve endothelial function.
• Modulate inflammatory response.
• Main plaque stability.
• Prevent blood clot formation.

It also increased the level of HDL (Good cholesterol) and reduces triglycerides.

How to take Rosuvastatin?

The drug is available in the form of a tablet.

• Strength – 5 mg, 10 mg, 20 mg.
• Initial dose– 5 mg one time in a day.
• Maximum dose – 40 mg daily.
• Children < 8 years– safety and efficacy not established.
• Children 8 to < 10 years – 5-10 mg in a day.
• 10-17 years of age – 5 to 20 mg per day. Maximum dose 20 mg daily.

The doctor may adjust the dose as the effect and how it is tolerated by patient at intervals of at least 2-4 weeks.

What are the uses of Rosuvastatin?

• Lowers “bad” cholesterol.
• Lower the level of fats such as triglycerides, LDL.
• Raise “good” cholesterol (HDL).
• Reduces the amount of cholesterol made by the liver.
• Decrease the risk of heart disease.
• Helps prevent strokes and heart attacks.
• Your Doctor may prescribe it for other uses not mentioned in medication guide.

What is the Precaution in taking Rosuvastatin?

• Certain conditions may create a problem. While taking this tablet. Ask or inform your doctor if you are/have.
• Allergic to above tablet.
• Any other allergies.
• Other medicines you take. This may avoid interaction of drugs.
• Pregnant
• Breast Feeding
• Having dental or any other surgery.
• Hospitalized due to serious injury or infection.
• Take alcohol.
• Take any anticoagulant 2 hours before this drug.

Cost of Rosuvastatin (Generic & Brand)

Generic medicines are cheaper than the Brand ones. Brand medicines increase their cost due to many reasons. They include Brand name, packaging & pricing. Other reasons include the cost spend on research and development of the drug.

Generic medicines are ordered in bulk and do not include such costing. All these benefits are passed on to our customers.

Cost of Generic Rosuvastatin

• Pack of 30 tablets of 5 mg cost $ 16, per unit costs $ 0.53.
• Pack of 30 tablets of 10 mg costs $ 27, per unit costs $ 0.9.
• Pack of 30 tablets of 20 mg cost $ 54, per unit cost $ 1.8.

Cost of Brand Crestor.

• Per unit cost of 5 mg tablet, it is $ 9.17
• Per unit cost of 10 mg tablets is $ 9.16
• Per unit cost of the 20 mg tablet is $ 9.16.