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Treating HIV Infection in Adult With Protease Inhibitor

Food and drug administration (FDA) of US approved Indinavir as a prescription medicine for the treatment of HIV infection in adult. It can also used in combination with other HIV medicines.

It belongs to the class of HIV drugs called protease inhibitors (PIS). Taking it will block an HIV enzyme (protein) known as protease. It cannot cure HIV/AIDs, but it allow person to live healthier and longer. This drug is included in the list of most important medicine in basic health system.


Indinavir is also called as protease inhibitor. It has activity against HIV-1 and HIV-2 infection. Protease inhibitors block the part of HIV called protease. Protease is an enzyme that starts or increase the speed of multiplication of HIV virus. Due to PIs, protease is blocked and the multiplication of HIV virus stops or reduces. This in turn reduces the amount of HIV in the body.


  • It is an antiviral medicine.
  • It prevents the multiplication of HIV cells in your body.
  • It allows a HIV infected person to live longer and healthier life.
  • It is prescribed alone or in combination with other HIV medicines.
  • It will not cure AIDs, but helps to keep HIV from reproducing.
  • Destruction of immune system becomes slow. This helps to delay the other problems related to HIV or AIDS the disease.
  • Doctor may use for purpose that are not listed in medication guide.


Indinavir is available in the form of capsule of 400 mg strength. Take according to your healthcare provider.

General Dosage

-Adult: – 800 mg every eight hours around the clock.

-Children (0-17 years of age): –There are no evidence of safety to use this medicine in children.

You should take dose one hour prior to meal or two hours after the meal. Drink more of water along with the medicine to avoid kidney stone.

Your dose may depend on;

  • Your age.
  • How severe is your condition.
  • Other medical condition you have.
  • How you react to the first dose.


It is important to take certain precautions in taking this medicine;

  • There are no evidences of effect of it in person with kidney/liver disease.
  • Lifelong treatment is must, to keep HIV in control.
  • Take medicines on time. Don’t skip or miss the dose.
  • HIV virus reduces the immunity of a person. Medicines stops the multiplication of virus and can delay this stage for a longer period.
  • Don’t take two doses at one time.
  • Swallow as whole. Don’t crush the capsule.
  • Don’t take the drug with heavy meal of high calorie. 


The active ingredient is Indinavir in both brand and generic form. The mechanism of action is same. We have drug resources in bulk. We adopt other cost cutting measures too. This further reduces its cost as generic. All this allows us to provide you generic drug cheaper than brand.

Generic 400 mg cost $1.65 per unit price or $49.45 for a pack of 30 capsules. Cost of brand Crixivan (400 mg) capsule costs $2.87 per unit price or $120.52 for a pack of 30 capsules. Average national price in US pharmacy local price is $3.05 each pill.