Medication for Palliative Treatment of Advanced Prostate Cancer

Abarelix is an injectable suspension. It belongs to the group of drug known as gonadotropin releasing-hormone (GnRH) antagonists. It is used in the palliative treatment of advanced prostate cancer where no other treatment is available. It is primarily used in oncology. It works by reducing the amount of testosterone among patients with advanced symptomatic prostate cancer. Testosterone is involved in the growth of prostate cancer. Abarelix may also be used for other purposes as determined by your physician.

How to use Abarelix?

Abarelix is used as an injection into the muscle particularly the buttock by a qualified health care provider. The recommended dose is 100mg every 4 weeks. To get the most benefit, use Abarelix regularly. Abarelix comes with additional information for patients or medical guide. Read the guide carefully before using. If you intend to inject this drug at home, use it exactly as prescribed. The vials must be stored in room temperature away from direct heat and sunlight. For a missed dose, contact your doctor right away.

What are the side effects of Abarelix?

Some of the side effects are:

• Nausea and vomiting
• Sleep disturbance
• Breast enlargement
• Swelling of extremities
• Headache
• Diarrhea
• Fatigue
• Urinary tract infections
• Upper respiratory tract infections
• Hot flushes
• Back pain
• Breast pain
• Constipation
• Redness at the injection site

Serious side effects are:

• Allergic reaction (Doctors must observe the patients for at least 30 minutes after administration). Severe allergic reactions may include symptoms like hives, rash, itching, fainting, light-headedness and swelling of the mouth, face, lips, throat and eyelid.

Important Information

• Before using Abarelix tell your doctor if:
• You have liver problems
• Have osteoporosis
• Weighing more than 225 pounds
• Have an irregular heartbeat
• This drug is not suitable for women. Women who are pregnant must not use this medication for it may cause birth defects in an unborn baby.
• Abarelix may interact with other medications and supplements. Inform your doctor if you are taking any other medications.
• Monitor your testosterone blood level and prostate-specific antigen (PSA) regularly.
• This drug is not suitable for children.
• In case of an overdose, seek medical attention right away. Check also with your doctor if your symptoms will not improve or will become worse.
• Do not drive or operate machinery. This drug may make you dizzy. Driving while under this medication is a potentially dangerous action.
• Keep this product away from the reach of the children. Dispose of used needles and syringes properly after use.