Alitretinoin is a vitamin A derivative. It belongs to the group of drug known as retinoids. Retinoids are commonly used in skincare. Alitretinoin is a type of retinoid prescribed by dermatologists for the treatment of severe chronic hand eczema. It is used when all other potent corticosteroids ointment, creams or lotion and other measures such as avoiding irritants, allergens and protecting the skin have not been effective in controlling chronic long-term hand eczema.
Alitretinoin works by altering the activity of the immune system in the skin. It also has an anti-inflammatory effect. People with scaly and mostly dry thickened hand eczema are more likely to respond to this medication than people with moist and weeping blisters in the skin.
This medication should be prescribed only by a physician with experience in the use of a retinoid. The usual recommended dose is 10 mg to 30 mg per day. Take the soft gel capsule at the same time each day with a meal. The starting dose is 30 mg daily but your doctor may reduce your dose to 10 mg if an adverse reaction will occur. The treatment may last from 12 to 24 weeks depending on the response. If the symptom does not get better after 12 weeks of treatment, your doctor may decide whether you will continue with the treatment or not.
Some of the common side effects are:
Serious side effects are:
In case of serious side effects, stop taking the medication and seek medical attention right away.
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