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Side Effects of Alectinib and How to Use it

Alectinibis an anti-cancer medication. It belongs to the group of drug known as proteinkinase inhibitors. It is prescribed by doctors for the treatment of non-smallcell lung cancer that has spread to other parts of the body (NSCLC) due to adefect in a gene called anaplastic lymphoma kinase or ALK.

Alectinibis approved by the U.S FDA as a first-line treatment of positive non-small celllung cancer since 2017. It works by blocking chemicals in the body that causesthe cancer cells to grow and spread.  Thismedication is used when crizotinib treatment is unsuccessful.

How to use Alectinib?

Alectinibcomes as a tablet form that you need to take by mouth. Your dose is based onthe following:

  • Condition being treated
  • Body weight
  • Other medications
  • Other medical conditions

Therecommended dose for an adult is 600mg divided into 4 doses. Take thismedication twice a day or as directed by your physician. The maximum daily doseis 1200mg a day. Take it with a meal and plenty of water. Do not take more thanwhat is prescribed. If you vomit at your first dose, take your next dose at theregular time. Do not stop taking this medication unless you are instructed toby your physician. To reduce nausea, your doctor may prescribe anti-nauseamedication.

What are the side effects of Alectinib?

Some ofthe side effects are:

  • Low red blood count
  • Constipation
  • Bone and muscle pain,weakness
  • Slow heartbeat
  • Low blood calcium
  • Weakness
  • Increase creatinine level
  • High glucose level

Lesscommon side effects are:

  • Headache
  • Weight gain
  • Diarrhea
  • Cough
  • Vomiting
  • Back pain

Stoptaking the medication if you will experience any of the following side effects:

  • Liver problems with signslike dark urine, jaundice and pain in the upper right side of the stomach area
  • Lung problem with signslike fever, cough, trouble breathing and shortness of breath.
  • Tear in the intestines andstomach with signs like fever, chill, stomach pain and change in bowel habit)

Important Information

  • Patients with a heart conditionmust use this medication with caution. This drug can cause a very low heartrate.
  • Some patients mayexperience gastrointestinal perforation
  • Before using thismedication, tell your doctor if you are taking any other medications
  • Pregnant and breastfeedingwomen must not take this drug.
  • Avoid prolonged sunexposure.
  • Take plenty of fluidsevery day.
  • Get plenty of rest.

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